Search on: RECEPTOR, TIE-1 
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Descriptor English:   Receptor, TIE-1 
Descriptor Spanish:   Receptor TIE-1 
Descriptor Portuguese:   Receptor de TIE-1 
Synonyms English:   TIE1 Tyrosine Kinase
Receptor, TIE 1
TIE 1 Receptor Tyrosine Kinase
TIE-1 Receptor
Tyrosine Kinase, TIE1
TIE-1 Receptor Tyrosine Kinase  
Tree Number:   D08.811.913.696.620.682.725.400.925.249
D12.776.543.750.630.687.249
Definition English:   A TIE receptor found predominantly on ENDOTHELIAL CELLS. It is considered essential for vascular development and can form a heterodimer with the TIE-2 RECEPTOR. The TIE-1 receptor may play a role in regulating BLOOD VESSEL stability and maturation. 
Indexing Annotation English:   see SCR for organism-specific terms
History Note English:   2004; for TIE-1 RECEPTOR TYROSINE KINASE & TIE1 TYROSINE KINASE use RECEPTOR, TIE-1 (NM) 1993-2003 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   38228 
Unique Identifier:   D042810 

Occurrence in VHL:
 

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